Session Details

Advanced Practice Professionals* (APP) Track Session - Management of CRS toxicity or other reactions related to CAR therapy
Saturday, September 14, 2019 10:45 AM - 12:15 PM
Ballroom A

Valkal Bhatt, PharmD, BCOP, BCPS, Memorial Sloan Kettering Cancer Center, USA

Pumping the Breaks on CAR T cell Toxicities
Learning objectives:
•      Review the approved indications for use of chimeric antigen receptor (CAR) T cell therapy in hematologic malignancies
•      Describe the pathophysiology of cytokine release syndrome (CRS) and neurologic toxicities associated with CD-19 directed CAR-T cell products
•      Discuss onset, symptoms, and grading of CAR T cell related toxicities
•      Apply the new consensus grading for CRS and neurologic toxicity associated with immune effector cells (IEC)
•      Outline prevention and management strategies for toxicities associated with CAR T cell therapy

Christina Bachmeier, PharmD, BCOP, Moffitt Cancer Center, USA

Rebecca Gonzalez, PharmD, BCOP Moffitt Cancer Center, USA

Mariam Dam, DNP, APRN Moffitt Cancer Center, USA